The Administration for Strategic Preparedness and Response (ASPR) today announced an agreement of approximately $14 million for innovative manufacturing of active pharmaceutical ingredients in the United States, initially previewed last November as part of an effort to make more essential medicines in America to help mitigate drug shortages as a matter of national defense.
“The award we are announcing today enables a domestic supply chain that provides on-demand manufacturing for essential medicines,” said Assistant Secretary for Preparedness and Response Dawn O’Connell. “We are committed to using innovative and flexible domestic manufacturing to increase capacity and reduce reliance on foreign sources.”
The agreement is the first to be funded by ASPR's Center for Industrial Base Management and Supply Chain (IBMSC) under the Defense Production Act (DPA) Title III for manufacturing of key starting materials and active pharmaceutical ingredients.
Under the agreement, the API Innovation Center (APIIC), a non-profit coalition in St. Louis, Missouri, will modernize the manufacturing capacities across several sites within APIIC's consortium network. Specific project partners, including MilliporeSigma, the University of Missouri – St. Louis, Apertus Pharmaceuticals, and Mallinckrodt Specialty Generics, will lead the implementation of continuous flow manufacturing and other advanced processes to establish end-to-end supply chains for three essential medicines. APIIC will contribute an additional $2.4 million.
These manufacturing practices are better suited and more efficient for rapid response during national emergencies and so that meeting demand is easier and faster than with traditional manufacturing. The agreement includes submitting the necessary data to the U.S. Food and Drug Administration to become approved domestic API suppliers for pharmaceutical manufacturers.
ASPR's DPA Title III program targets investments that create, maintain, protect, expand, or restore domestic industrial base capabilities that are critical to preparing for and responding to both current and future public health emergencies.
The award was made through the Biopharmaceutical Manufacturing Preparedness Consortium ( BioMaP-Consortium ), managed by Advanced Technologies International under an Other Transaction Authority agreement with ASPR's Biomedical Advanced Research and Development Authority.
Within the U.S. Department of Health and Human Services, ASPR leads the nation's medical and public health preparedness for, response to, and recovery from disasters and other public health emergencies. ASPR collaborates with hospitals, healthcare coalitions, biotech firms, community members, state, local, tribal, and territorial governments, and other partners across the country to improve readiness and response capabilities.
'I am honored to be the first but I hope and pray that I am not the last,' Saraya Saber said of her historic bout as a trans woman.
Another historic first for pro wrestling is coming this weekend.
On Sunday, out trans wrestler Saraya Saber is set to challenge NWA World Women’s champion Kenzie Paige for her title at New South Pro Wrestling’s “ Action Clash ” event in Scottsboro, Ala., making her the first out trans female wrestler to challenge for the NWA’s top women’s championship in the organization’s 76-year history.
The importance of the moment isn’t lost on Saber, even if it is “a bit overwhelming.”
“I have been busting my butt for two years now and even then I never thought this match would happen,” Saber told Outsports. “I know, in the grand scheme of things, it is only a small step, but to be able to say that, in over 70 years of the NWA, I get to be the first trans woman to challenge for this title is still crazy.
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“When I started wrestling, I often wondered if there would ever even be a place for me as a trans woman in the South, but for there to not only be a place but somewhere like New South that is giving me this opportunity to do something that most of the country probably wouldn’t like, it really makes me feel like we’re doing something special.”
FIRST TRANS WOMAN TO CHALLENGE FOR THE NWA WOMENS WORLD TITLE…… ITS F'ING SABER TIME!!!! https://t.co/6vewJD1zDy — Saraya Saber (@SarayaSaber) September 11, 2024
Saber’s title match makes her only the second out trans wrestler to battle for any NWA championship and the third out trans wrestler to feature in an NWA-associated match, joining reigning NWA World TV champion Max The Impaler and Jamie Senegal .
The then-NWA Unified World TV champion, Max relinquished their NWA World Women’s TV title in order to face Paige for her title at the company’s “NWA 76” event last month. It was the out non-binary transmasculine wrestler’s second opportunity at the title since joining the NWA in 2022. They additionally challenged for the NWA World Women’s Tag Team titles with Angelina Love in 2023.
Senegal competed in the inaugural Mildred Burke Invitational match at the company’s “NWA EmPowerrr” event in August 2021.
While the groundbreaking nature of the match resonates with Saber both personally and professionally, she views it as much more than something just for herself.
“I have a promo planned where I say ‘I fight for every trans person who came before me and every trans person who come after me,’ and I mean that,” she said. “I am honored to be the first but I hope and pray that I am not the last. Hopefully, by having this match, it can show those who thought they would never have a space in this business that they can do it and they belong here.”
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COMMENTS
Guidelines for essay titles in Chicago Manual of Style format. Chicago style also requires that essay titles be in title case. Other than that, Chicago style doesn't have specific guidelines for what a title should or shouldn't include. Here is an example of an essay title in Chicago style: 2021 Returns: What We Projected vs. Actual Returns
7 10 Tips to Create an Exceptional Title. 7.1 Questions make Catchy. 7.2 Describe the Paper in 5 Words. 7.3 Use One Direct Word. 7.4 Extract a Sentence from the Paper. 7.5 Take advantage of Pop-Culture. 7.6 Put "On" at the beginning. 7.7 Start with a Verb in "-ing". 7.8 Give a Mental Visualization of Your Topic.
Here are other rules for how to create a good title: Title every section of writing: In the process of writing, create interesting subheadings to give your paragraphs an identity. Also, they make your text look ordered and clear. The title must bear the theme of the text: choose a title that summarizes the essay. Capitalize all words with certain exceptions: Capitalize the first letter of ...
Use title case, which means capitalizing the first and last words of the title and all major words in between (e.g., The Art of Writing: Crafting Engaging Essays). Do not underline, italicize, or use quotation marks for the title. It's common to use a 12-point Times New Roman font. Example:
Consider Your Audience: Take into account the target audience for your essay. Consider their interests, knowledge level, and expectations. Tailor your title to resonate with your specific readership. A title that speaks directly to your audience's needs and desires will be more effective in capturing their attention.
Writing effective headings. Although similar, headings are not the same as titles. Headings head paragraphs and help structure a document. Effective headings make your paper easily scannable. Common high level headings in dissertations and research papers are "Methods", "Research results", and "Discussion". Lower level headings are ...
Taking the time to craft great titles and headers can advance your writing to the next level. Count words and characters, correct spelling and grammar, and check keyword density. Don't overlook the title and section headers when putting together your next writing assignment. Follow these pointers for keeping your writing organized and effective.
Tip #1: Keep the Title Simple and Precise. You want your title to be easy to read and consume. So using complex words in this section will only go a long way to ruin the effort you put to writing a comprehensive and compelling essay.
English Essay Titles Examples. Writing a title for an English essay doesn't have to be boring. In fact, if you're studying literature, you should take the opportunity to flex your creative writing skills. Don't overdo it though! Titles still need to be predictive, comprehensible, and engaging. Examples down below. Akala: A Modern Day ...
Crafting a good title requires a blend of creativity, precision, and strategic thinking. To create an effective title, consider the following tips: Brainstorm Ideas: Begin by brainstorming keywords, phrases, and concepts related to your essay topic. Explore different angles and perspectives that encapsulate the essence of your argument or analysis.
If the source is independent, italicize the title. Write the titles of books, films, websites, and magazines in italics. If the paper belongs to a larger piece of work, add the quotation marks. Writers use them for articles, websites, essays, and songs.
The most common and basic technique is to get a title from the summary of your essay. A writer can summarize the entire essay or the central idea and thesis statement in three words and write a title. This can be a title by putting it in a headline, inserting a colon, and stating the purpose of your essay. 7.
Capitalize the first and final word of the title. Capitalize nouns, pronouns, verbs, helping verbs, adjectives and adverbs within the title. Capitalize the first word that follows a colon when using title case. Do not capitalize articles located between the first and final words, such as "the," "a" and "an."
The title of any paper should reveal: What the paper is about. Cover the general idea of your work in the title. Why the reader might be interested in it. Prove the relevance of your paper to the audience. The context of the issue. A good title previews the full picture of the topic regarding its "when" and "where.".
At College Essay Guy, we too like good stories well told. The problem is that sometimes students have really good stories … that just aren't well told. They have the seed of an idea and the makings of a great story, but the essay formatting or structure is all over the place. Which can lead a college admissions reader to see you as ...
Create an effective title for each paper containing such a thesis statement: (1) Thesis statement: In film, men are always portrayed as tough, macho figures, and this image ultimately harms men as they are forced to live up to this aggressive, emotionless "ideal.". Possible Title (s): (2) Thesis statement: Because the media depicts men and ...
Come up with a thesis. Create an essay outline. Write the introduction. Write the main body, organized into paragraphs. Write the conclusion. Evaluate the overall organization. Revise the content of each paragraph. Proofread your essay or use a Grammar Checker for language errors. Use a plagiarism checker.
If the titles are on the same line, separate them by a colon. If not, you don't need the colon. 4. Check for keywords. Make sure you've included as many of your keywords as possible. If your keywords are essential to your paper, they're essential to your title, too. [10] Compare your title to the list you made earlier.
rafts. Effective titles often pull words or phrases from the essay in which t. used. Avoid using clichéd phras. s as titles. For example, "Beauty is Pain" is an overused phrase that has little impact. Below are a few examples of real, interesting titles from existing works: hter" Question: "Where Are You Going, Where Have.
Titles such as "Puking on the President," "Romeo's Ripped Tights," and "The Wrong Goal" are sure to pique your reader's interest. Simple and direct language can also be quite effective. Consider, for example, "The Job I Should Have Quit" by Drew, "Wallflower" by Eileen, and "Striking Out" by Richard.
Use quotation marks around the title if it is part of a larger work (e.g. a chapter of a book, an article in a journal, or a page on a website). All major words in a title are capitalized. The same format is used in the Works Cited list and in the text itself. Place in quotation marks. Italicize.
The Essay Title Generator is an AI-based tool that creates original and thought-provoking essay titles. By analyzing your input keywords or themes, it generates a range of titles suitable for various academic disciplines and writing styles. This tool is a helpful resource for students and writers looking to create titles that accurately reflect ...
The Cure May Have Confirmed the Title and Release Date of a New Album. Speculation is mounting that the band's 14th studio album is arriving in the coming months. By Thomas Smith. Thomas Smith ...
Most topics are acceptable for college essays if you can use them to demonstrate personal growth or a lesson learned. However, there are a few difficult topics for college essays that should be avoided. Avoid topics that are: Overly personal (e.g. graphic details of illness or injury, romantic or sexual relationships)
The Administration for Strategic Preparedness and Response (ASPR) today announced an agreement of approximately $14 million for innovative manufacturing of active pharmaceutical ingredients in the United States, initially previewed last November as part of an effort to make more essential medicines in America to help mitigate drug shortages as a matter of national defense.
Saber's title match makes her only the second out trans wrestler to battle for any NWA championship and the third out trans wrestler to feature in an NWA-associated match, joining reigning NWA ...