NCI funds and oversees both early- and late-phase clinical trials to develop new treatments and improve patient care. Trials are available for breast cancer prevention, screening, and treatment. Breast Cancer Research Results. The following are some of our latest news articles on breast cancer research and study updates:
New study finds triple-negative breast cancer tumors with an increase
By Kelley Luckstein. A new multicenter, international study suggests that people who have early-stage triple-negative breast cancer (TNBC) and high levels of immune cells within their tumors may have a lower risk of recurrence and better survival rates even when not treated with chemotherapy. The study was published today in the Journal of American Medical Association (JAMA).
Breast Cancer Research Articles
Posted: January 20, 2023. Many young women who are diagnosed with early-stage breast cancer want to become pregnant in the future. New research suggests that these women may be able to pause their hormone therapy for up to 2 years as they try to get pregnant without raising the risk of a recurrence in the short term.
Articles
Breast cancer (BC) is a highly prevalent malignancy worldwide, with complex pathogenesis and treatment challenges. Research reveals that methyltransferase-like 3 (METTL3) is widely involved in the pathogenesis... Dongqiong Xiao, Mingfu Zhang, Yi Qu and Xiaojuan Su. Breast Cancer Research 2024 26 :110.
Breast cancer
Read the latest Research articles in Breast cancer from Nature. ... An analysis of 780 breast cancer genomes shows that focal amplifications are frequently preceded by dicentric chromosome ...
Breast cancer
Breast cancer is the most common cancer in women, but it can also appear in men. Featured AI-assisted detection of lymph node metastases safely reduces costs and time
Estrogen a more powerful breast cancer culprit than we realized
Estrogen is already known to fuel breast cancer growth by promoting the proliferation of breast cells. However, the new observations cast this hormone in a different light. They show estrogen is a more central character in cancer genesis because it directly alters how cells repair their DNA. The findings suggest that estrogen-suppressing drugs ...
Immunotherapy in breast cancer: an overview of current ...
Recent progress in immunobiology has led the way to successful host immunity enhancement against breast cancer. In triple-negative breast cancer, the combination of cancer immunotherapy based on ...
Experimental immunotherapy targets metastatic breast cancer
An experimental form of immunotherapy that uses an individual's own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute's (NCI) Center for Cancer Research, part of the National Institutes of Health.
Breast Cancer Treatments: Updates and New Challenges
New Strategies and Challenges for Breast Cancer Treatment. 4.1. Emerging Therapies for HR-Positive Breast Cancer. As mentioned in Section 3.1, the major mechanisms of action of current endocrine therapy resistance occur via (1) the mTOR/PI3K/Akt signaling pathway and (2) the actors of the cell cycle progression CDK4/6.
Breast cancer: an up-to-date review and future perspectives
1 INCIDENCE AND EPIDEMIOLOGY OF BREAST CANCER. Female breast cancer has overtaken lung cancer as the most common diagnosed cancer worldwide. The estimated new breast cancer cases reached 2.3 million in 2020, accounting for 11.7% of all new cancers, and 684,996 cases died of it [].In China, breast cancer was the most common malignancy among women, with an estimated number of 306,000 new cases ...
What's New in Breast Cancer
HER2 is a common treatment target for breast cancer. This new drug targets HER3, a biomarker related to HER2, which is associated with poor breast cancer outcomes. About 10% to 20% of newly diagnosed breast cancers are HER2-positive. At the 2023 American Society for Clinical Oncology (ASCO) Annual Meeting, researchers announced positive results ...
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Breast Cancer Research is an international, peer-reviewed online journal, publishing original research, reviews, editorials and reports. Open access research articles of exceptional interest are published in all areas of biology and medicine relevant to breast cancer, including normal mammary gland biology, with special emphasis on the genetic, biochemical, and cellular basis of breast cancer.
Strongest contender in decades in fight against breast cancer
For decades, hormonal treatment of breast cancer has been going in one direction -- blocking estrogen. ... Your source for the latest research news. Follow: Facebook X/Twitter Subscribe: RSS Feeds.
Breast Cancer Drug Trial Results in 'Unheard-Of' Survival
One patient in the current study, Mary Smrekar, age 55, of Medina, Ohio, said she felt she got a temporary reprieve from certain death. ... Citing rising breast cancer rates in young women, ...
PDF Breast Cancer Facts & Figures 2022-2024
Mortality. The overall breast cancer death rate increased by 0.4% per year from 1975 to 1989, but since has decreased steadily, for a total decline of 43% through 2020. As a result, 460,000 breast cancer deaths were averted in US women from 1989 through 2020.
Breast Cancer News -- ScienceDaily
Breast cancer research including information on breast cancer symptoms, prevention strategies, screening techniques, and new breast cancer treatments. ... 2024 — Current screening protocols fail ...
Research News
Find out what the latest clinical trial results mean for you. More from this topic. Targeted Therapy 76. Risk Factors 78. Hormonal Therapy 47. Healthcare Disparities 14. Genetic Testing 16. Diagnosis 206. View all 25 topics. 469 Research news. Filter & Sort ... Having a family history of breast cancer and a mutation in any of the five main ...
Genetic testing advances help women with high risk of breast cancer
Researchers involved in BRIDGES and B-CAST—another research initiative—have made huge advances in showing how both genes, lifestyle and environmental factors influence the risk of breast ...
Study Highlights Molecular Targets for Breast Cancer Treatment
It's estimated that over 281,000 women in the U.S. will be diagnosed with breast cancer this year, according to the National Cancer Institute. And about one in seven women will receive a breast cancer diagnosis in their lifetime. For those with breast cancer gene 2 (BRCA2) mutations, the risk of developing breast cancer is much higher. Between 45 and 69 percent of those with this genetic ...
Researchers reveal impact of genetic ancestry on breast cancer risk and
In a recent study published in Nature Medicine, researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk. Study ...
Targeting HER2-positive breast cancer: advances and future directions
The discovery of the monoclonal antibody trastuzumab almost 25 years ago revolutionized treatment and drug development for HER2+ breast cancer. Here, Swain et al. review the current standard of ...
AI in Breast Cancer Drug Development and Trials
The final installment of BCRF's series on AI in breast cancer focuses on how it can bring new treatments to patients—faster. Artificial Intelligence (AI) is already having a transformative impact in healthcare, including on breast cancer detection and diagnosis, risk assessment, and prognosis.And there is much excitement building around AI's potential role in drug discovery and clinical ...
Reproductive Concerns Among Young Adult Women With Breast Cancer: A
Objectives: Systemic cancer treatments pose threats to fertility, leading to concerns regarding fertility and parenthood in young adult women with breast cancer (YAWBC). This systematic review aimed to synthesize existing evidence on reproductive concerns (RCs) among YAWBC and identify areas where further research in needed.
Comparison of incident breast cancer cases in the largest national US
CONFLICT OF INTEREST STATEMENT. Jennifer K. Plichta is a recipient of research funding by the Color Foundation; is a member of Editorial Committee for the American Joint Committee on Cancer (AJCC), the Breast Panel for the AJCC, and the National Comprehensive Cancer Network (NCCN) Breast Cancer Diagnosis and Screening panel; and reports grant and/or contract funding from the National ...
Effect of Messaging on Support for Breast Cancer Screening Cessation
Importance Many older women are screened for breast cancer beyond guideline-recommended thresholds. Messaging holds promise to reduce overscreening. Objective To investigate the effect of a message on older women's support for and intentions of stopping breast cancer screening.. Design, Setting, and Participants A 2-wave randomized clinical online survey trial using a nationally ...
Research News
Black, Hispanic Survivors of Breast Cancer Have Higher Death Rates from Second Cancers Liquid Biopsy Predicts Early Disease Progression, Potential Survival in Patients with Advanced Breast Cancer Natural Compounds Derived from Soy and Other Plants Reduce Breast Cancer Recurrence and Improve Survival, Research Shows
Registration for Breast Cancer Surgery Webinar Now Open
Patient education and surgical breast cancer experts will review current practices in breast cancer surgical care, including pain management, lymphedema prevention, and wound care. In addition, easy-to-use educational programs and checklists that are aligned with the National Accreditation Program for Breast Centers (NAPBC) standards will be ...
Flaxseeds and Breast Cancer
Phytoestrogens and breast cancer treatment. Tamoxifen is a medication known as a selective estrogen receptor modulator, or SERM. Tamoxifen often is prescribed as part of the treatment for ER+ breast cancer. Tamoxifen binds with estrogen receptors, without activating growth in breast cancer cells.
Problem Solvers Caucus Endorses Garbarino Bill to Improve Care for
WASHINGTON, D.C. - Today, the bipartisan Problem Solvers Caucus announced its endorsement of the Metastatic Breast Cancer Access to Care Act, legislation that will eliminate waiting periods for federal disability insurance benefits and Medicare coverage for individuals undergoing treatment for metastatic breast cancer.. Metastatic breast cancer is an advanced-stage IV breast cancer that ...
COMMENTS
NCI funds and oversees both early- and late-phase clinical trials to develop new treatments and improve patient care. Trials are available for breast cancer prevention, screening, and treatment. Breast Cancer Research Results. The following are some of our latest news articles on breast cancer research and study updates:
By Kelley Luckstein. A new multicenter, international study suggests that people who have early-stage triple-negative breast cancer (TNBC) and high levels of immune cells within their tumors may have a lower risk of recurrence and better survival rates even when not treated with chemotherapy. The study was published today in the Journal of American Medical Association (JAMA).
Posted: January 20, 2023. Many young women who are diagnosed with early-stage breast cancer want to become pregnant in the future. New research suggests that these women may be able to pause their hormone therapy for up to 2 years as they try to get pregnant without raising the risk of a recurrence in the short term.
Breast cancer (BC) is a highly prevalent malignancy worldwide, with complex pathogenesis and treatment challenges. Research reveals that methyltransferase-like 3 (METTL3) is widely involved in the pathogenesis... Dongqiong Xiao, Mingfu Zhang, Yi Qu and Xiaojuan Su. Breast Cancer Research 2024 26 :110.
Read the latest Research articles in Breast cancer from Nature. ... An analysis of 780 breast cancer genomes shows that focal amplifications are frequently preceded by dicentric chromosome ...
Breast cancer is the most common cancer in women, but it can also appear in men. Featured AI-assisted detection of lymph node metastases safely reduces costs and time
Estrogen is already known to fuel breast cancer growth by promoting the proliferation of breast cells. However, the new observations cast this hormone in a different light. They show estrogen is a more central character in cancer genesis because it directly alters how cells repair their DNA. The findings suggest that estrogen-suppressing drugs ...
Recent progress in immunobiology has led the way to successful host immunity enhancement against breast cancer. In triple-negative breast cancer, the combination of cancer immunotherapy based on ...
An experimental form of immunotherapy that uses an individual's own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute's (NCI) Center for Cancer Research, part of the National Institutes of Health.
New Strategies and Challenges for Breast Cancer Treatment. 4.1. Emerging Therapies for HR-Positive Breast Cancer. As mentioned in Section 3.1, the major mechanisms of action of current endocrine therapy resistance occur via (1) the mTOR/PI3K/Akt signaling pathway and (2) the actors of the cell cycle progression CDK4/6.
1 INCIDENCE AND EPIDEMIOLOGY OF BREAST CANCER. Female breast cancer has overtaken lung cancer as the most common diagnosed cancer worldwide. The estimated new breast cancer cases reached 2.3 million in 2020, accounting for 11.7% of all new cancers, and 684,996 cases died of it [].In China, breast cancer was the most common malignancy among women, with an estimated number of 306,000 new cases ...
HER2 is a common treatment target for breast cancer. This new drug targets HER3, a biomarker related to HER2, which is associated with poor breast cancer outcomes. About 10% to 20% of newly diagnosed breast cancers are HER2-positive. At the 2023 American Society for Clinical Oncology (ASCO) Annual Meeting, researchers announced positive results ...
Breast Cancer Research is an international, peer-reviewed online journal, publishing original research, reviews, editorials and reports. Open access research articles of exceptional interest are published in all areas of biology and medicine relevant to breast cancer, including normal mammary gland biology, with special emphasis on the genetic, biochemical, and cellular basis of breast cancer.
For decades, hormonal treatment of breast cancer has been going in one direction -- blocking estrogen. ... Your source for the latest research news. Follow: Facebook X/Twitter Subscribe: RSS Feeds.
One patient in the current study, Mary Smrekar, age 55, of Medina, Ohio, said she felt she got a temporary reprieve from certain death. ... Citing rising breast cancer rates in young women, ...
Mortality. The overall breast cancer death rate increased by 0.4% per year from 1975 to 1989, but since has decreased steadily, for a total decline of 43% through 2020. As a result, 460,000 breast cancer deaths were averted in US women from 1989 through 2020.
Breast cancer research including information on breast cancer symptoms, prevention strategies, screening techniques, and new breast cancer treatments. ... 2024 — Current screening protocols fail ...
Find out what the latest clinical trial results mean for you. More from this topic. Targeted Therapy 76. Risk Factors 78. Hormonal Therapy 47. Healthcare Disparities 14. Genetic Testing 16. Diagnosis 206. View all 25 topics. 469 Research news. Filter & Sort ... Having a family history of breast cancer and a mutation in any of the five main ...
Researchers involved in BRIDGES and B-CAST—another research initiative—have made huge advances in showing how both genes, lifestyle and environmental factors influence the risk of breast ...
It's estimated that over 281,000 women in the U.S. will be diagnosed with breast cancer this year, according to the National Cancer Institute. And about one in seven women will receive a breast cancer diagnosis in their lifetime. For those with breast cancer gene 2 (BRCA2) mutations, the risk of developing breast cancer is much higher. Between 45 and 69 percent of those with this genetic ...
In a recent study published in Nature Medicine, researchers map the diverse cell types present in healthy breast tissue to elucidate the role of genetic ancestry in breast cancer risk. Study ...
The discovery of the monoclonal antibody trastuzumab almost 25 years ago revolutionized treatment and drug development for HER2+ breast cancer. Here, Swain et al. review the current standard of ...
The final installment of BCRF's series on AI in breast cancer focuses on how it can bring new treatments to patients—faster. Artificial Intelligence (AI) is already having a transformative impact in healthcare, including on breast cancer detection and diagnosis, risk assessment, and prognosis.And there is much excitement building around AI's potential role in drug discovery and clinical ...
Objectives: Systemic cancer treatments pose threats to fertility, leading to concerns regarding fertility and parenthood in young adult women with breast cancer (YAWBC). This systematic review aimed to synthesize existing evidence on reproductive concerns (RCs) among YAWBC and identify areas where further research in needed.
CONFLICT OF INTEREST STATEMENT. Jennifer K. Plichta is a recipient of research funding by the Color Foundation; is a member of Editorial Committee for the American Joint Committee on Cancer (AJCC), the Breast Panel for the AJCC, and the National Comprehensive Cancer Network (NCCN) Breast Cancer Diagnosis and Screening panel; and reports grant and/or contract funding from the National ...
Importance Many older women are screened for breast cancer beyond guideline-recommended thresholds. Messaging holds promise to reduce overscreening. Objective To investigate the effect of a message on older women's support for and intentions of stopping breast cancer screening.. Design, Setting, and Participants A 2-wave randomized clinical online survey trial using a nationally ...
Black, Hispanic Survivors of Breast Cancer Have Higher Death Rates from Second Cancers Liquid Biopsy Predicts Early Disease Progression, Potential Survival in Patients with Advanced Breast Cancer Natural Compounds Derived from Soy and Other Plants Reduce Breast Cancer Recurrence and Improve Survival, Research Shows
Patient education and surgical breast cancer experts will review current practices in breast cancer surgical care, including pain management, lymphedema prevention, and wound care. In addition, easy-to-use educational programs and checklists that are aligned with the National Accreditation Program for Breast Centers (NAPBC) standards will be ...
Phytoestrogens and breast cancer treatment. Tamoxifen is a medication known as a selective estrogen receptor modulator, or SERM. Tamoxifen often is prescribed as part of the treatment for ER+ breast cancer. Tamoxifen binds with estrogen receptors, without activating growth in breast cancer cells.
WASHINGTON, D.C. - Today, the bipartisan Problem Solvers Caucus announced its endorsement of the Metastatic Breast Cancer Access to Care Act, legislation that will eliminate waiting periods for federal disability insurance benefits and Medicare coverage for individuals undergoing treatment for metastatic breast cancer.. Metastatic breast cancer is an advanced-stage IV breast cancer that ...